Early differences in fecal microbiota composition in children may predict overweight

TABLE 2

Bacterial counts in fecal samples analyzed by fluorescent in situ hybridization during infancy

Normal-weight children Overweight children Mann-Whitney U test
Bifidobacteria (×109 cells/g)
    6 mo 2.47 (1.52–4.21) [16]1 1.46 (0.35–2.35) [23]
    12 mo 0.70 (0.39–1.69) [19] 0.20 (0.14–0.88) [22]
    During infancy2 1.62 (1.01–3.73) [14] 1.05 (0.61–1.38) [20] 0.08
Bacteroides (×108 cells/g)
    6 mo 0.62 (0.12–3.05) [16] 0.83 (0.24–2.28) [23]
    12 mo 0.43 (0.13–2.50) [19] 0.91 (0.39–4.45) [22]
    During infancy2 0.96 (0.24–4.0) [14] 1.26 (0.49–2.77) [20] 0.44
Lactobacilli (×108 cells/g)
    6 mo 3.26 (0.57–8.25) [16] 1.14 (0.60–2.54) [23]
    12 mo 1.20 (0.64–2.30) [19] 1.13 (0.26–2.76) [22]
    During infancy2 2.46 (1.24–4.59) [14] 1.43 (0.82–2.23) [20] 0.11
Clostridia (×108 cells/g)
    6 mo 0.91 (0.38–3.63) [16] 0.73 (0.24–1.78) [23]
    12 mo 1.48 (0.44–5.87) [19] 0.45 (0.065–2.78) [22]
    During infancy2 2.18 (1.18–3.74) [14] 1.49 (0.39–2.45) [20] 0.15
Total cell count (×109 cells/g)
    6 mo 5.47 (3.43–10.10) [16] 3.52 (2.26–5.09) [23]
    12 mo 3.44 (2.07–10.35) [19] 3.22 (1.96–5.03) [22]
    During infancy2 4.44 (2.68–9.39) [14] 3.54 (2.27–5.11) [20] 0.29

  • ↵1 Median; interquartile range in parentheses; n in brackets (all such values).

  • ↵2 The mean bacterial number was obtained by dividing the sum of the bacterial numbers at 6 and 12 mo by 2.

This Article

  1. Am J Clin Nutr vol. 87 no. 3 534-538
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